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目的:观察左炔诺孕酮和来非司酮用于紧急避孕的有效性、副反应及对月经的影响。方法:对214例要求72小时内紧急送孕的妇女以2:1随机分为二级。一组(LNG组)144例.口服左炔诺孕酮0.75mg.隔12小时再重复1次同样剂量;另一组(Mife组)70例.单次口服术非司酮25mg。结果:LNG组妊娠5例,失败率为3.47%,避孕有效率60.1%:Mife组妊娠1例,失败率1.42%.避孕有效率80.2%。二组服药后月经改变少.主诉有轻度恶心、头晕、乏力等到反应者LNG组占22.2%,Mife组24.3%。结论:左炔语孕酮或来非司酮都是有效的紧急避孕方法。
Objective: To observe the effectiveness of levonorgestrel and nifepristone in emergency contraception, side effects and their effects on menstruation. METHODS: A total of 214 women requiring urgent delivery within 72 hours were randomized to two levels at 2: 1. One group (LNG group) 144 cases. Levonorgestrel 0.75 mg orally. The same dose was repeated once every 12 hours; the other group (Mife group) 70 cases. A single oral administration of aspirin 25mg. Results: LNG group 5 cases of pregnancy, the failure rate was 3.47%, the contraceptive efficiency of 60.1%: Mife group of pregnancy in 1 case, the failure rate of 1.42%. Effective contraception 80.2%. Two groups after menstruation medication changes less. The chief complaint was mild nausea, dizziness, weakness until the responders LNG group accounted for 22.2%, Mife group 24.3%. CONCLUSIONS: Left prion progesterone or nifepristone are both effective emergency contraception methods.