概述肝昏迷又称肝性脑病(Hepatic encephalopathy),源于严重肝功能损害,不能清除血中有毒代谢产物;或因建立门—腔静脉侧枝循环后门脉血有毒物质绕过肝脏,进入体循环内导致中枢神经系统代谢与功能障碍。患者出现一系列精神神经症状,直至昏迷。鉴于近年肝炎流行较为严重,肝昏迷病人屡见不鲜。本文就肝昏迷发病机理和防治措施从生化角度予以阐明,供临床参考。一、肝昏迷的分类与比较 Summary Hepatic coma, also known as Hepatic encephalopathy, is caused by severe liver damage and can not remove toxic metabolites in the blood. After establishing portal-venous collateral circulation, toxic substances in portal blood bypass the liver and enter the systemic circulation Causes central nervous system metabolism and dysfunction. The patient developed a series of neurotic symptoms until unconscious. In view of the more serious hepatitis epidemic in recent years, hepatic coma patients are uncommon. This article on the pathogenesis of hepatic coma and prevention measures from the biochemical point of view to clarify for clinical reference. First, the classification and comparison of hepatic coma