为确定医护人员全程接种疫苗后是否出现免疫,有必要检查抗-HBs。如未检出抗-HBs,则需考虑是否有现行HBV感染。换言之,HBV现行感染与抗-HBs是相互排斥的,然而一些研究报道HBV感染可与抗-HBs同时出现。为研究这一现象,本文回顾性分析同时存在HBsAg和抗-HBs的荷兰个案病例。 It is necessary to check for anti-HBs in order to determine whether immunization occurs after the full vaccination of health care workers. If no anti-HBs are detected, consider whether there is an existing HBV infection. In other words, current HBV infection and anti-HBs are mutually exclusive, however, some studies have reported that HBV infection can occur concurrently with anti-HBs. In order to study this phenomenon, we retrospectively analyzed the cases of Dutch patients with both HBsAg and anti-HBs.