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益母草作为一种传统的妇科中药,近年来的研究表明其作用是多方面的。在心血管方面,益母草能改善心肌缺血、增加冠状动脉血流、提高心功能,其机制主要是在氧化应激状态下通过清除氧自由基、抑制活性氧簇生成发挥抗氧化作用。益母草心脏保护作用的另一机制是促进血管发生。临床试验也表明,益母草能抑制冠心病人的血小板聚集,起抗凝、抗血栓形成作用,从而改善血流变学参数。本文根据目前研究进展,对益母草的心脏保护作用简要综述。
Motherwort as a traditional gynecological medicine, recent research shows that its role is multi-faceted. In the cardiovascular aspect, Motherwort can improve myocardial ischemia, increase coronary blood flow, and improve heart function. Its mechanism is mainly to play an antioxidant role by scavenging oxygen free radicals and inhibiting the production of reactive oxygen species under oxidative stress. Another mechanism of cardioprotective effect of Motherwort is to promote angiogenesis. Clinical trials have also shown that Motherwort can inhibit platelet aggregation in patients with coronary heart disease, play an anticoagulant, antithrombotic effect, thereby improving blood rheology parameters. Based on the current research progress, this article briefly reviews the cardioprotective effects of Motherwort.