原癌基因c-fos在中枢的表达被视为伤害性刺激的标志物。本文首次报道电针刺激亦可在大鼠脊髓诱发c-fos的表达。我们采用c-fos的蛋白产物Fos抗体的免疫反应活性(Fos-like immunoreactivity,FLI)来间接反映c-fos的表达。实验在雌性Wistar大鼠上进行。给予大鼠一侧后肢“三阴交”穴位100 Hz电针30分钟(1-3 mA),2小时后灌流、固定动物,取脊髓腰 The expression of proto-oncogene c-fos in the central nervous system is considered as a noxious stimulus marker. This paper reports for the first time that electroacupuncture stimulation may also induce c-fos expression in the spinal cord of rats. We used c-fos protein product Fos antibody immunosuppressive activity (Fos-like immunoreactivity, FLI) to indirectly reflect the c-fos expression. Experiments were performed on female Wistar rats. Rats were given a hind limb “Sanyinjiao” acupuncture points 100 Hz EA for 30 minutes (1-3 mA), 2 hours after perfusion, fixed animals, spinal cord