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目的:比较极低出生体质量儿(VLBWI)的两种微量喂养方法的效果。方法:将66例VLBWI随机分成两组,治疗组35例,对照组31例,经口胃管微泵输注微量母乳,前者持续2 h,后者持续15 min,均2 h喂奶一次,视情况加奶并逐渐改经口喂养,观察两组喂养不耐受、恢复至出生体质量时间、达完全肠内喂养时间。结果:治疗组的喂养不耐受率11.4%,对照组38.7%,两组比较差异有统计学意义(P<0.05),治疗组在恢复至出生体质量时间、达到完全肠内喂养时间分别为(10.38±2.83)d、(8.47±2.25)d,均明显短于对照组的(11.75±1.64)d、(9.56±1.83)d,两组比较,差异有统计学意义(P<0.05)。结论:在经口胃管间断性持续微泵输注微量母乳的两种方法中,每次持续2 h比持续15 min的方法更有利于VLBWI的胃肠道成熟、减少喂养不耐受、缩短完全胃肠内喂养时间及恢复至出生体质量时间。
Objectives: To compare the effects of two micronutrient feeding methods with very low birth weight (VLBWI). Methods: Sixty-six patients with VLBWI were randomly divided into two groups: 35 cases in the treatment group and 31 cases in the control group. The micro-pump of oral gastric tube was used to transfuse breast milk. The former sustained for 2 hours and the latter sustained for 15 minutes. The situation with milk and gradually changed to oral feeding, observation of two groups intolerance, recovery to birth weight time, up to completely enteral feeding time. Results: Infertility was 11.4% in the treatment group and 38.7% in the control group, with significant difference between the two groups (P <0.05). The recovery time to birth weight of the treatment group was (10.38 ± 2.83) d and (8.47 ± 2.25) d, respectively, which were significantly shorter than those in the control group (11.75 ± 1.64) days and (9.56 ± 1.83) days respectively. There was significant difference between the two groups (P <0.05). CONCLUSION: In the two methods of intermittent micro-pump infusion of oral micro-parenteral nutrition in gastric mucosa, duration of 2 h each for 15 min is more beneficial to gastrointestinal maturation of VLBWI, reducing feeding intolerance and shortening Complete gastrointestinal feeding time and recovery to birth weight time.