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以炎症性肠病的临床症状为基础,结合实验室检查进行记分来评价疾病活动性的方法比较麻烦,且敏感性不高。因此需要一种客观的判断指标,特别在用以对新药作出评价时,可避免各种症状变异对疗效的干扰。本文旨在探讨~(99m)锝标记的吞噬细胞扫描是否为判断炎症性肠病(IBD)活动性的有效方法。材料和方法:51例患者中(年龄16～70岁),35例是克隆病,16例为溃疡性结肠炎。8例腹痛、腹泻病例经粪检、结肠镜及多块活检证实无感染或炎症性肠病,作为对照组。以克隆病活动指标和粘膜活检组织学分级
Based on the clinical symptoms of inflammatory bowel disease, a combination of laboratory tests to score the disease activity evaluation method is too much trouble, and the sensitivity is not high. Therefore, an objective judgmental index is needed, especially when it is used to evaluate new drugs to avoid the interference of various symptoms and variations on the curative effect. This article aims to investigate whether ~ (99m) technetium-labeled phagocyte scanning is an effective method to determine the activity of inflammatory bowel disease (IBD). Materials and Methods: Of the 51 patients (aged 16-70 years), 35 were Crohn’s disease and 16 were ulcerative colitis. 8 cases of abdominal pain, diarrhea cases by fecal examination, colonoscopy and biopsy confirmed no infection or inflammatory bowel disease, as a control group. Clonal disease index and mucosal biopsy histological grading