论文部分内容阅读
目的通过对该院妊娠期急性脂肪肝(AFLP)患者的回顾分析,总结治疗经验,为降低病死率,提高母婴生存率提供依据。方法回顾分析2010年3月-2016年9月在该院治疗的20例AFLP患者,将其分成生存组13例及死亡组7例,对比两组发病到终止妊娠的时间和治疗方案,从而得出积极的治疗方法。结果 20例患者均发生在孕晚期,经产妇2例,初产妇18例。自发病起7 d内终止妊娠的患者生存率为69%,超过7 d终止妊娠的患者生存率为33%。生存组中2例患者在发生肝性脑病后1 d进行血浆置换;死亡组中1例患者在发生肝性脑病后4 d进行血浆置换。结论早期诊断,积极终止妊娠,术后早期行人工肝治疗,可提高母婴生存率。
Objective To summarize the experience of treatment by analyzing and analyzing the patients with acute fatty liver during pregnancy in our hospital and to provide the basis for reducing the mortality and improving the survival rate of maternal and infant. Methods A retrospective analysis of 20 AFLP patients treated in our hospital from March 2010 to September 2016 was divided into survival group (n = 13) and death group (n = 7). The time and treatment of onset to termination of pregnancy were compared between the two groups A positive treatment. Results All the 20 patients occurred in the third trimester of pregnancy, including 2 maternal and 18 primipara. Survival was 69% for patients who terminated their pregnancies within 7 days of onset, and 33% for those who terminated pregnancies beyond 7 days. Two patients in the survival group underwent plasma exchange one day after hepatic encephalopathy; one patient died in the plasma exchange after 4 days of hepatic encephalopathy. Conclusion Early diagnosis, positive termination of pregnancy, early postoperative artificial liver treatment can improve maternal and child survival.