目的探讨无创正压通气治疗慢性阻塞性肺疾病致呼吸衰竭的疗效及临床分析。方法 2010年05月至2012年05月期间,我院诊治的64例慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭患者,随机分为对照组(常规治疗)和观察组(常规治疗基础上,给予无创正压通气治疗),每组各32例,对两组患者治疗前后PH、动脉氧分压,以及二氧化碳分压等指标,进行观察和比较。结果治疗72h后,与对照组相比,观察组动脉氧分压明显升高,二氧化碳分压明显降低,P<0.05,差异有统计学意义。结论对于慢性阻塞性肺疾病并发Ⅱ型呼吸衰竭患者,常规治疗基础上,进行无创正压通气治疗疗效显著,明显改善患者的呼吸功能,提高患者的预后质量,值得临床推广。 Objective To investigate the curative effect and clinical analysis of non-invasive positive pressure ventilation on respiratory failure caused by chronic obstructive pulmonary disease. Methods From May 2010 to May 2012, 64 patients with chronic obstructive pulmonary disease (COPD) type Ⅱ respiratory failure treated in our hospital were randomly divided into control group (conventional treatment) and observation group (on the basis of routine treatment, non-invasive Positive pressure ventilation treatment), 32 cases in each group, before and after treatment of PH, arterial oxygen pressure, and carbon dioxide partial pressure and other indicators were observed and compared. Results 72h after treatment, compared with the control group, the observation group arterial oxygen pressure increased significantly, carbon dioxide partial pressure decreased significantly, P <0.05, the difference was statistically significant. Conclusion For chronic obstructive pulmonary disease patients with type Ⅱ respiratory failure, on the basis of routine treatment, noninvasive positive pressure ventilation has a significant curative effect, significantly improving the patient’s respiratory function and improving the quality of prognosis of the patients, which is worthy of clinical promotion.