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为研究阿芦宝C片的润肠通便作用,进行了动物研究。结果表明与阴性对照组相比,阿芦宝C片剂量为0 .9 、1 .8 g/kg BW 时,对小鼠小肠蠕动有显著促进作用( P< 0 .05) ,并能显著缩短小鼠排便时间和增加粪便中的水分含量( P< 0 .05) ;其剂量为1 .8 g/kg BW 时,能显著增加小鼠排便粒数及粪便干、湿重( P< 0 .05) ;阿芦宝C片0 .2 、0 .4、0 .8 mg/mL3 个浓度剂量能明显地增强家兔十二指肠和空肠自发性收缩,表现为振幅加大、张力增加( P< 0.01),并对阿托品引起的十二指肠和空肠收缩运动抑制有明显的拮抗作用
In order to study the effect of laxative effect of Alubao C tablets, animal studies were conducted. The results showed that compared with the negative control group, the amount of aloebao C tablets was 0. 9, 1 . At 8 g/kg BW, the intestinal peristalsis of mice was significantly promoted (P < 0.05), and the mice’s defecation time and fecal moisture content were significantly shortened (P < 0.05); 1 . When 8 g/kg BW, the number of defecation pellets and feces dry and wet weights were significantly increased (P<0.05); Aluobao C tablets 0. 2, 0. 4,0. The concentration of 8 mg/mL 3 doses can significantly increase the spontaneous contraction of duodenum and jejunum in rabbits, with the increase of amplitude and tension (P<0.01), and the duodenum and jejunum caused by atropine. Suppression of contractile movement has obvious antagonism