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目的:观察患有恶性肿瘤HIV阳性患者CD3+,CD3+ CD4+,CD3+ CD8+,CD3+ CD4+/CD3+ CD8+比值变化的临床意义。方法:回顾分析2008-01/2010-02在本院就诊的各类肿瘤并HIV阳性患者35例检测其T细胞亚群水平对疾病的诊断及预后判断的意义。结果:观察组患者T细胞亚群水平与健康对照组比较外周血CD3+,CD3+ CD4+细胞比例及CD3+ CD4+/CD3+ CD8+比值明显低于健康对照组水平(P<0.01),而CD3+ CD8+细胞比例明显高于健康对照组(P<0.01)。结论:检测肿瘤HIV阳性患者的细胞免疫T细胞亚群水平,有助于对疾病的诊断及预后判断。
Objective: To observe the clinical significance of the change of the ratio of CD3 +, CD3 + CD4 +, CD3 + CD8 +, CD3 + CD4 + / CD3 + CD8 + in HIV positive patients with malignant tumor. Methods: The significance of detecting T cell subsets in 35 cases of all kinds of tumors and HIV positive patients treated in our hospital from January 2008 to January 2010 in the diagnosis and prognosis of the disease was retrospectively analyzed. Results: The ratio of CD3 +, CD3 + CD4 + cells and the ratio of CD3 + CD4 + / CD3 + CD8 + were significantly lower in the observation group than those in the healthy control group (P <0.01), while the proportion of CD3 + CD8 + cells in the observation group was significantly higher than that in the healthy control group In healthy control group (P <0.01). Conclusion: Detecting the level of cellular immune T lymphocyte subsets in HIV-positive patients is helpful for the diagnosis and prognosis of the disease.