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透射电镜下观察PAR 20例。其发作期鼻粘膜的病理学特征是:上皮纤毛损害,上皮间隙扩大,上皮胞浆线粒体、粗面内质网和吞饮小泡增多;上皮下和固有层组织水肿,小血管和毛细血管扩张,腔内血浆和血细胞成分淤滞,毛细血管内皮和周细胞吞饮小泡增多,内皮连接间隙扩大;多量嗜酸粒细胞浸润和肥大细胞脱颗粒,浆细胞增多:浆液腺体增生和分泌亢进。结合病理学所见对PAR的发病机理和病理生理学作简要讨论。
TEM observation of 20 cases of PAR. The pathological features of the nasal mucosa during its attack are: epithelial cilia damage, epithelial space expansion, epithelial cytoplasmic mitochondria, rough endoplasmic reticulum and swallowed vesicles increased; epithelial and lamina propria edema, small blood vessels and telangiectasias , Intracavitary plasma and blood cell components stasis, capillary endothelium and pericytes swallowed vesicles increased, endothelial connectivity gap to expand; a large number of eosinophil infiltration and mast cell degranulation, plasma cells increased: serous gland hyperplasia and secretion of hyperthyroidism. Combined with pathology seen on the pathogenesis of PAR and pathophysiology for a brief discussion.