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胺碘酮是目前临床应用最广泛的抗心律失常药物之一,近年来国内有文献报道,本品可致肝损害,现概述如下:兰安杰等报道,患女,69岁,因心律失常给予胺碘酮150mg静注,30分钟后出现窦性心动过缓,低血压,予对症治疗1小时后症状缓解。后因心动过速发作再次给予本品300mg+5%GS50ml以0.6mg/min泵入,次日查肝功能示:ALT1770U/L,AST1360U/L,TBil130.2umol/L,DBil98.4umol/L,停
Amiodarone is currently one of the most widely used clinical anti-arrhythmic drugs, in recent years, there are reports in the literature, this product can cause liver damage, are summarized as follows: Lan Anjie et al reported that women, 69 years old, due to arrhythmia Give intravenous amiodarone 150mg, 30 minutes after sinus bradycardia, hypotension, to symptomatic treatment 1 hour after the symptoms were relieved. After the tachycardia attack again give the product 300mg +5% GS50ml to 0.6mg / min pumped into the next day check liver function showed: ALT1770U / L, AST1360U / L, TBil130.2umol / L, DBil98.4umol / L, stop