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PEDF 是最近发现的一种神经营养因子,在许多组织均由表达。它具有强大的营养和保护神经作用。已有研究显示其作用机制主要涉及 N-端结构域,改变细胞内钙离子,影响其它因子和胶质细胞而发挥作用等等。它对于神经疾病的治疗可能具有很大的潜力。
PEDF is a recently discovered neurotrophic factor that is expressed in many tissues. It has a strong nutritional and neuroprotective effects. Studies have shown that its mechanism of action mainly involves the N-terminal domain, changes in intracellular calcium, affecting other factors and glial cells and so on. It may have great potential for the treatment of neurological diseases.