目的　观察双侧髂内动脉插管化疗药物灌注及栓塞治疗妇科恶性肿瘤的疗效。方法　对 2 8例妇科恶性肿瘤进行双侧髂内动脉插管灌注化疗药物并进行栓塞。结果　 2 8例患者共 81次介入治疗 ,最少 1次 ,最多 6次。CR 2例 ,PR11例 ,MR 9例 ,SD 1例 ,PD 3例 ,无法评价疗效 2例。有效率 (CR +PR)为 5 0 .0 % ( 13/ 2 6 )。半年存活 2 3例 ,占 88.5 % ;1年存活 19例 ,占 73.1% ;2年存活 8例 ,占 30 .8%。结论　髂内动脉插管化疗药物灌注及栓塞术对妇科中晚期恶性肿瘤可限制其发展 ,减轻痛苦 ,延长生命 ,提高生存质量 ,为一种有效的姑息疗法 Objective To observe the curative effect of bilateral internal iliac artery infusion chemotherapy and chemotherapy on gynecologic malignancies. Methods Twenty-eight gynecological malignancies were infused with bilateral internal iliac artery for chemotherapeutic drugs and embolized. Results 28 patients received a total of 81 interventions, at least 1, up to 6 times. 2 cases of CR, 11 cases of PR, 9 cases of MR, 1 case of SD, 3 cases of PD, and 2 cases failed to evaluate the curative effect. The effective rate (CR + PR) was 50.0% (13/2 6). Six months survived in 23 cases, accounting for 88.5%. One year survived in 19 cases, accounting for 73.1%. Two years survived in 8 cases, accounting for 30.8%. Conclusion Intra-iliac artery chemotherapy and drug infusion and embolization of advanced gynecological malignancy can limit its development, reduce pain, prolong life and improve the quality of life, as an effective palliative treatment