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为确定子宫内膜异位症(EMs)妇女腹腔液表皮生长因子(EGF)含量随着疾病的严重程度及不孕症的有无而改变的规律性,对75例妇女的腹腔液进行研究。其中25例为外在性EMs(Ⅰ～Ⅱ期13例,Ⅲ～Ⅳ期12例)的可生育妇女(1组),32例为外在性EMs(Ⅰ～Ⅱ期20例,Ⅲ～Ⅳ期12例)并发不孕症(除外其它原因所致)妇女(2组),3组(对照组)为18例健康可生育妇女。全部妇女均行腹腔镜检查,确定外在性EMs的诊断及病变严重程度,同时采集腹腔液,应用免疫酶分析法检测腹腔液EGF浓度,所得资料经统计学处理。
In order to determine the regularity of the changes of peritoneal fluid epidermal growth factor (EGF) levels in women with endometriosis (EMs) according to the severity of the disease and the presence or absence of infertility, 75 women with peritoneal fluid were studied. Twenty-five of them were fertile women (group 1) with extrinsic EMs (13 cases in stage Ⅰ ~ Ⅱ and 12 cases in stage Ⅲ ~ Ⅳ) and 32 cases were extrinsic EMs (20 cases in stage Ⅰ ~ Ⅱ, Ⅲ ~ Ⅳ Period 12 cases) infertility (except for other causes) of women (2 groups), 3 groups (control group) for 18 cases of healthy fertile women. All women underwent laparoscopy to determine the diagnosis of exogenous EMs and the severity of the lesion. Meanwhile, the peritoneal fluid was collected and the concentration of EGF in peritoneal fluid was detected by the enzyme immunoassay. The data obtained were statistically analyzed.