因肿瘤进行化疗的育龄妇女常以口服避孕药作为避孕方法。由于化疗能导致骨髓抑制,使用低剂量复方口服避孕药可以减少患者的月经失血量。此外,使用口服避孕药后有规律的撤退性出血可使患者及其医生对月经有足够的准备。而且,复发性白血病患者因化疗引起全血细胞减少的时间过长时,常需用口服避孕药造成人工闭经。然而,除出血外,化疗的另一个常见并发症是出血性粘液性结肠炎。这类患者可因体内药物排泄而突发大量撤退性出血,因此不宜口服给药,需选择其它给药途径。本文报告1例急性早幼粒细胞性白血病患者阴道用口服避孕药控制月经出血的病例。患者18岁妇女,既往健康,无妊娠史,于1986年10月因拔牙后出血时间延长而就诊。当时白细胞总数50000,未成熟细胞>50%。1987年11月26日骨髓穿刺证实为急性早幼粒细胞性白血病并给予阿 Women of childbearing age who have undergone chemotherapy for cancer often use oral contraceptives as a method of contraception. As chemotherapy can lead to bone marrow suppression, the use of low-dose oral contraceptives can reduce the amount of menstrual blood loss. In addition, regular withdrawal bleeding after oral contraceptives allows the patient and his doctor to have adequate menstrual preparation. Moreover, patients with relapsed leukemia due to chemotherapy-induced pancytopenia over time, often require oral contraceptives caused by artificial amenorrhea. However, in addition to bleeding, another common complication of chemotherapy is hemorrhagic mucinous colitis. Such patients may be excreted by the body due to a large number of drug evacuated bleeding, it should not be oral administration, need to choose other routes of administration. This article reports 1 case of acute promyelocytic leukemia vaginal oral contraceptives to control menstrual bleeding cases. 18-year-old woman, past health, no history of pregnancy, in October 1986 due to prolonged bleeding after extraction and treatment. At that time, the total number of white blood cells 50000, immature cells> 50%. November 26, 1987 bone marrow puncture confirmed acute promyelocytic leukemia and given a