目的定量研究敌敌畏中毒血液灌流吸附毒物的清除效率。方法采用HA230树脂吸附柱对中毒血样进行灌流吸附,将灌流吸附后血样经乙酸乙酯萃取后,用气相色谱法测定其含量。结果方法的加标回收率为89.3%～96.6%,RSD为4.82%～5.99%。经HA230型树脂灌流吸附,血中敌敌畏清除效率为67.1%～84.7%。结论血液经HA230型树脂灌流吸附,能清除大部分毒物,迅速降低血中敌敌畏的浓度,对抢救重度敌敌畏中毒的危重病人有重要价值。 Objective To quantitatively study the removal efficiencies of adsorbed poisons from blood perfusion of dichlorvos poisoning. Methods The poisoned blood samples were adsorbed on HA230 resin column. The blood samples were extracted with ethyl acetate after perfusion, and their contents were determined by gas chromatography. Results The spiked recoveries of the method were 89.3% ~ 96.6% with RSDs of 4.82% ~ 5.99%. After HA230 resin perfusion adsorption, the removal efficiency of dichlorvos in blood was 67.1% ~ 84.7%. Conclusion The blood is absorbed by HA230 resin, which can remove most of the poison and rapidly reduce the concentration of dichlorvos in the blood. It is of great value to rescue critically ill patients with severe dichlorvos poisoning.