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目的：说明肾移植中供受者之间ＨＬＡ配型的重要意义并探讨其可行性。方法：采用国际统一的方法，即补体依赖性微量淋巴细胞毒实验和微量淋巴细胞毒供受者交叉实验方法，对汉族人１０８例等待肾移植的病人和３７例供者的ＨＬＡ－Ａ、Ｂ、ＤＲ和ＤＱ位点进行抗原分型。结果：２、３、４、５和６个抗原相合者分别为１０７、１０６、８９、３７和２例，说明ＨＬＡ相合率地区实测值明显高于理论值。１例供受者间ＨＬＡ有３个抗原相合者，移植后１ｈ出现排尿反应，另１例全不合，移植后２４天内无排尿反应，移植失败。结论：ＨＬＡ相合与否对肾移植成败至关重要。在一个地区、一个民族范围内比较容易找到ＨＬＡ部分相合的供者
OBJECTIVE: To demonstrate the importance of HLA matching among donors in renal transplantation and to explore their feasibility. Methods: HLA-A, B (108 cases) and kidney donors (38 cases) were enrolled in this study. The methods of complementarity-dependent microlymphocytotoxicity and microtiter lymphotoxin donor / , DR and DQ sites for antigen typing. Results: The coincidences of 2, 3, 4, 5 and 6 antigens were 107, 106, 89, 37 and 2 respectively, indicating that the measured area of HLA coincidence rate was significantly higher than the theoretical value. One patient had HLA matched with three antigens, and a voided reaction occurred at 1h after transplantation. The other patients were totally incompatible. There was no voiding reaction within 24 days after transplantation, and the transplantation failed. Conclusion: HLA matching or not is crucial for the success or failure of renal transplantation. In one area, it is easier to find HLA partially compatible donors within a nation