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目的了解深圳市某玩具厂苯作业工人非酒精性脂肪肝和颈动脉粥样硬化的患病情况,分析非酒精性脂肪肝与颈动脉粥样硬化的关系。方法选取2015年在深圳市龙岗区平湖预防保健所参加职业健康检查的某玩具厂苯作业工人1 556例,对其肝、颈动脉超声检查结果进行分析。结果苯作业工人中非酒精性脂肪肝的检出率为16.07%,颈动脉粥样硬化的检出率为12.21%。非酒精性脂肪肝组与正常肝组工人颈动脉粥样硬化检出率分别为19.6%、10.8%,差异有统计学意义(χ~2=15.171,P<0.01)。>50岁年龄组非酒精性脂肪肝人群颈动脉粥样硬化检出率显著高于正常肝人群(P<0.01)。结论苯作业工人非酒精性脂肪肝人群的颈动脉粥样硬化检出率明显高于正常肝人群,特别应警惕50岁以上人群动脉粥样硬化和心脑血管事件的发生,及时进行必要的干预和治疗。
Objective To understand the prevalence of nonalcoholic fatty liver disease and carotid atherosclerosis among benzene workers in a toy factory in Shenzhen and to analyze the relationship between nonalcoholic fatty liver disease and carotid atherosclerosis. Methods A total of 1 556 benzene workers at a toy factory in a toy factory participated in occupational health examination at Pinghu Institute of Preventive Medicine, Longgang District, Shenzhen in 2015 were selected to analyze the results of ultrasonography of liver and carotid arteries. Results The detection rate of non-alcoholic fatty liver in benzene workers was 16.07%, and the detection rate of carotid atherosclerosis was 12.21%. The detection rates of carotid atherosclerosis in non-alcoholic fatty liver group and normal liver group were 19.6% and 10.8%, respectively, with significant difference (χ ~ 2 = 15.171, P <0.01). The detection rate of carotid atherosclerosis in> 50-year-old nonalcoholic fatty liver was significantly higher than that in normal liver (P <0.01). Conclusions The detection rate of carotid atherosclerosis in benzene-exposed non-alcoholic fatty liver patients is significantly higher than that in normal liver patients. In particular, we should be alert to the occurrence of atherosclerosis and cardiovascular and cerebrovascular events in people over 50 years of age and make the necessary intervention in time And treatment.