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目的分析衡水地区无偿献血者的梅毒感染情况,采取有效措施,确保血液安全。方法对衡水地区2010-2013年无偿献血者血液采用ELISA方法对梅毒螺旋体抗体(抗-TP)进行筛查。抗-TP阳性检测结果分别按照性别、年龄、年份、职业统计分析。结果 2010-2013年梅毒阳性感染者有370人份,女性的梅毒阳性率(0.42%)明显高于男性(0.26%),差异有统计学意义(χ2=14.99,P<0.05)。梅毒感染增长趋势明显,2013年最高达到0.45%,不同年份间梅毒感染差异有统计学意义(χ2=46.93,P<0.05)。自由职业、工人、农民是梅毒感染的主要群体。梅毒感染主要集中在31~40岁。结论梅毒感染呈快速增长趋势,应加强梅毒相关知识的宣传,扩大低危献血人群,把梅毒的金标试剂列为血站采血前初筛常规检测项目,减少血液报废,保证血液质量。
Objective To analyze syphilis infection in blood donors in Hengshui area and take effective measures to ensure blood safety. Methods Treponema pallidum antibody (anti-TP) was screened by ELISA in the blood of unpaid blood donors from 2010 to 2013 in Hengshui. Anti-TP positive test results were in accordance with gender, age, year, occupational statistics analysis. Results The number of syphilis positive persons in 2010-2013 was 370, and the positive rate of syphilis in female was 0.42%, significantly higher than that of male (0.26%) (χ2 = 14.99, P <0.05). Syphilis infection increased significantly, up to 0.45% in 2013, with significant differences in syphilis infections in different years (χ2 = 46.93, P <0.05). Freelance workers, peasants are the major group of syphilis infections. Syphilis infections are mainly concentrated in 31 to 40 years old. Conclusion Syphilis infection shows a trend of rapid growth. Propaganda of syphilis should be strengthened to expand the population of low-risk blood donors. The gold standard of syphilis should be listed as a routine screening test before blood collection in blood stations to reduce blood waste and ensure blood quality.