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将20只家兔随机等份分成A组(喂清鱼油)和B组(喂浓鱼油),对用药前后的眼压、眼压描记及房水cAMP和cGMP值进行同组对比和两组间的比较。结果:(1)A、B两组用药14天后眼压分别下降0.76±0.17和0.92±0.20kPa。(2)A、B两组用药13天后C值分别升高0.09±0.02和0.08±0.04,B组F值下降1.04±0.09。(3)A、B两组用药14天后房水cAMP和cGMP分别升高1.36±2.21、1.95±3.34和5.92±3.96、3.12±2.43pmol/ml。因此认为鱼油通过影响兔房水生成和排出降眼压并与其房水cAMP和cGMP含量改变有关。
Twenty rabbits were randomly divided into group A (fed with fish oil) and group B (fed fish oil), the intraocular pressure, intraocular pressure, and cAMP and cGMP values of aqueous humor before and after treatment were compared in the same group and between two groups Comparison. Results: (1) The intraocular pressure of group A and group B dropped 0.76 ± 0.17 and 0.92 ± 0.20kPa respectively after 14 days. (2) The values of C in group A and group B increased by 0.09 ± 0.02 and 0.08 ± 0.04 respectively after 13 days of treatment, and the value of F in group B decreased by 1.04 ± 0.09. (3) The cAMP and cGMP of aqueous humor in A and B groups increased by 1.36 ± 2.21, 1.95 ± 3.34 and 5.92 ± 3.96, 3.12 ± 2.43 pmol / Ml. So that fish oil through the impact of rabbit aqueous humor formation and discharge of intraocular pressure and its aqueous humor cAMP and cGMP content changes.