论文部分内容阅读
目的 探讨18F 氟代脱氧葡萄糖正电子发射计算机断层摄影术 (FDGPET)对非小细胞肺癌 (NSCLC)术前分期的准确性及其应用价值。方法 对 82例经病理证实的NSCLC患者胸部CT扫描、全身FDGPET显像和病理检查资料进行回顾性分析。结果 82例NSCLC患者肺部病灶及转移灶部位FDG摄取均增高。FDGPET对预测NSCLC纵隔淋巴结转移的敏感性为 94.4% ,特异性为 10 0 % ;对探测胸外转移灶的敏感性明显高于CT。 42例患者手术治疗的结果证实 ,FDGPET对NSCLC的分期准确性达 95 .2 %。经全身FDGPET显像 ,82例患者中 37例 (45 .1% )的CT分期得到改变 ,为患者治疗方案的选择提供了重要依据。结论 FDGPET在NSCLC的术前分期方面优于CT等常规检查 ,但在精确定位方面仍然需要结合解剖显像技术。
Objective To investigate the accuracy and value of 18F fluorodeoxyglucose positron emission computed tomography (FDGPET) in preoperative staging of non-small cell lung cancer (NSCLC). Methods A total of 82 cases of pathologically confirmed NSCLC patients were retrospectively analyzed by chest CT scan, whole body FDG PET imaging and pathological examination. Results FDG uptake was increased in the lung lesions and metastatic lesions in 82 NSCLC patients. The sensitivity of FDGPET in predicting NSCLC mediastinal lymph node metastasis was 94.4% and specificity was 100%. The sensitivity of detection of extrathoracic metastases was significantly higher than that of CT. The results of surgical treatment of 42 patients confirmed that the accuracy of FDG PET on NSCLC was 95.2%. Through whole-body FDG PET imaging, the CT staging of 37 (45.1%) of the 82 patients was changed, providing an important basis for the choice of patient treatment options. Conclusions FDGPET is superior to CT and other routine examinations in the preoperative staging of NSCLC, but it still requires the combination of anatomical imaging techniques for precise positioning.