甲氧萘丙酸是一种非类固醇抗炎药物,具有镇痛、退热的特性,常用于治疗关节疾患,还可用作退热剂。作者研究甲氧萘丙酸对癌症患者的退热效果,评价该药区别肿瘤发热还是感染发热的功效。16例最近诊断为恶性肿瘤及肿瘤复发的患儿,全部处在活动期,有不明原因的发热,按受了甲氧萘丙酸治疗。尽管合理使用抗生素、血培养阴性,但仍表现为持续发热,72小时后用甲氧萘两酸治疗。其适应症如下:(1)体温在38.3℃以上;(2)持续发热达72小时;(3)临床及实验室检查无感染证据;(4)胸部X线照片阴性。其剂量7.5mg/kg/次, Naproxen is a non-steroidal anti-inflammatory drug with analgesic and antipyretic properties commonly used in the treatment of joint disorders and as an antipyretic. The authors studied the effect of naproxen on cancer patients in the antipyretic effect of the drug to assess the difference between the fever or infection of the efficacy of fever. 16 cases of newly diagnosed malignant tumors and tumor recurrence in children, all at active stage, with unknown causes of fever, according to the treatment by naproxen. Despite the rational use of antibiotics, blood cultures were negative but continued to develop fever and were treated with naproxen 72 hours later. The indications are as follows: (1) body temperature above 38.3 ℃; (2) sustained fever for 72 hours; (3) clinical and laboratory evidence of no evidence of infection; (4) chest X-ray negative. The dose of 7.5mg / kg / time,