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目的探讨H型高血压对老年糖尿病性脑梗死预后的影响。方法将我院收治的70例老年糖尿病性脑梗死患者根据是否合并H型高血压分为观察组和对照组,观察组为H型高血压脑梗死合并糖尿病患者,对照组为单纯老年高血压糖尿病性脑梗死患者。2组均给予脑梗死对症治疗,采用NIHSS、mRS、BI评价2组患者预后情况。结果 2组治疗前收缩压、舒张压比较差异无统计学意义(P>0.05)。观察组治疗前Hcy浓度显著高于对照组,观察组治疗后Hcy略低于治疗前,观察组与对照组治疗前NISS、mRS、BI评分差异无统计学意义,对照组治疗90d后NISSH、mRS、BI评分显著优于观察组,观察组复发率显著高于对照组(P<0.05)。结论合并H型高血压的老年糖尿病性脑梗死患者神经功能缺损程度更加严重,预后不佳,高Hcy影响老年糖尿病性脑梗死患者预后的机制还有待进一步研究。
Objective To investigate the effect of Hypertension on the prognosis of senile diabetic cerebral infarction. Methods Seventy patients with senile diabetic cerebral infarction admitted to our hospital were divided into observation group and control group according to whether they had Hypertension or not. The observation group was Hypertensive cerebral infarction with diabetes mellitus. The control group was simple elderly hypertensive diabetic Patients with cerebral infarction. Two groups were given symptomatic treatment of cerebral infarction, NIHSS, mRS, BI evaluation of two groups of patients with prognosis. Results Before treatment, systolic blood pressure and diastolic blood pressure had no significant difference (P> 0.05). The Hcy concentration in the observation group before treatment was significantly higher than that in the control group. Hcy in the observation group was slightly lower than that before the treatment. There was no significant difference in NISS, mRS and BI before observation in the observation group and in the control group. After 90 days of treatment, , BI score was significantly better than the observation group, the observation group recurrence rate was significantly higher than the control group (P <0.05). Conclusions Elderly patients with Hypertension have more severe neurological deficits and poor prognosis. The mechanism of high Hcy affecting the prognosis of elderly patients with diabetic cerebral infarction remains to be further studied.