4—硝基烷酸酯不仅是制备氨基酸、氨基醇、γ—内酯和二氢茉莉酮等物质的有效中间体,且在合成树脂、增塑剂和药物的制备方面也有着广泛的用途。文献报道的合成方法,主要是在有机溶剂中,于无机碱或低分子有机碱的作用下,使具有α—H的硝代烃与α,β—不饱和醋进行共轭加成而获得。但以具有多个α—H的硝代烃进行反应时,可发生多重Michael加成 4-Nitro-alkanoates are not only useful intermediates for the preparation of amino acids, aminoalcohols, γ-lactones and dihydrojasmone, but also have a wide range of uses in the production of synthetic resins, plasticizers and pharmaceuticals. Synthetic methods reported in the literature, mainly in organic solvents, in the inorganic base or low molecular weight organic base, the α-H with the nitro-hydrocarbon and α, β-unsaturated vinegar conjugated to obtain. However, multiple Michael additions can occur when reacting with nitro-hydrocarbons having multiple α-H