生漆(国漆)是我国特产的一种天然涂料,已具四千余年历史。其化学成分主要是漆酚、漆酶、胶质、水和其它少量有机物,是一种“油包水”型的乳胶漆。众所周知,生物体(人或动物)接触生漆后,可引起过敏性或接触性皮炎已无异议;但有关其经口和经皮毒性实验报道罕见,为此进行本实验的研究。急性经口毒性实验小鼠一次经口观察二周后的LD_(50)为1.80(95％可信范围1.62～1.87)毫升/公斤,属低毒类物质。急性中毒症状主要表现开始有烦躁不安、打呃、反胃、食欲减退、腹部胀气、以后静趴、呼吸缓慢,以至死亡;一般动物在24小时(最短3小时)内, Lacquer (Guoqi) is a natural paint of our country, with a history of more than 4000 years. Its chemical composition is mainly urushiol, laccase, gum, water and other small amounts of organic matter, is a “water-in-oil” type of latex paint. It is well-known that organisms that can cause allergic or contact dermatitis after exposure to raw lacquer have no objection; however, oral and transdermal toxicity experiments are rarely reported and the study of this study was conducted for this purpose. Acute oral toxicity of oral mice once observed after two weeks LD_ (50) was 1.80 (95% confidence range 1.62 to 1.87) ml / kg, is a low-toxic substances. The main symptoms of acute poisoning start with restlessness, hit uh, nausea, loss of appetite, abdominal flatulence, after lying quietly, breathing slowly and even death; general animal in 24 hours (minimum 3 hours)