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目的：３０例接受顺铂或阿霉素加环磷酰胺联合化疗病人，采用随机、交叉、自身对照方法，观察口服康泉的止吐作用，并同时与静脉康泉比较，观察两者的疗效和毒性。方法：口服康泉１ｍｇ，ｂｉｄ，静脉康泉３ｍｇ，静脉冲入，ｑｄ。结果：对顺铂所致呕吐，口服康泉总有效率为７８６％，完全控制率５７１％；静脉康泉总有效率及完全控制率均为６４３％。对非顺铂所致呕吐，口服及静脉康泉的有效率均为９３８％，完全控制率分别为８７５％、８１２％。结论：口服康泉能有效预防中度致吐化疗药所致呕吐，其疗效与静脉康泉相似，且口服安全，有效，方便，更适合门诊病人。
OBJECTIVE: To observe the antiemetic effect of Oral Kangquan by randomized, crossover and self-control method in 30 patients who received cisplatin or doxorubicin combined with cyclophosphamide chemotherapy. At the same time, compared with intravenous Kangquan, the curative effect was observed And toxicity. Methods: oral health Stephen 1mg, bid, intravenous Kangquan 3mg, intravenous infiltration, qd. Results: For cisplatin-induced vomiting, the total effective rate was 78.6% and the complete control rate was 571%. The total effective rate and complete control rate of intravenous Kangquan were 643%. Efficacy of non-cisplatin-induced vomiting, oral and intravenous health springs were 93 8%, the complete control rates were 87 5%, 81 2%. Conclusion: Oral Kangquan can effectively prevent vomiting induced by moderately emetogenic chemotherapeutic drugs. Its curative effect is similar to that of intravenous Kangquan, and it is safe, effective, convenient and suitable for outpatients.