选择28例(男26,女2)单纯矽肺患者,皆脱离粉尘接触5年以上,并且均未曾在铜、锌厂矿工作过的职业史。对照组为39名(男25,女14)无粉尘接触史的健康成人。经血清铜、锌检测,健康成人性别之间无显著性差异。而中晚期矽肺患者血清铜含量明显高于对照;血清锌明显低于对照;铜 Select 28 cases (male 26, female 2) patients with simple silicosis, all from the dust exposure to more than 5 years, and have not worked in the copper, zinc mines occupational history. The control group consisted of 39 healthy men (25 men and 14 women) with no history of exposure to dust. The serum copper, zinc test, no significant difference between healthy adult gender. Serum copper levels in patients with advanced silicosis were significantly higher than those in controls; serum zinc was significantly lower than that in controls; copper