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目的:探讨宫颈环形电切术(leep术)对宫颈上皮内瘤变(CIN)的治疗价值。方法:对通过阴道镜及宫颈活检初步诊断为CINⅠ～Ⅲ的患者进行leep锥切治疗,观察手术时间、术中出血量、术后病理结果与术前结果符合率、术后随访宫颈复原情况并对其临床疗效进行回顾性分析。结果:leep术治疗CIN的平均时间为5.6 min,出血量为7.8 ml。术前术后病理诊断符合率为72.4%,病理级别上升率为4.0%,病理级别下降率为23.6%。术后668例患者中(除去5例行子宫切除加2例行广泛子宫切除加盆腔淋巴结清扫术)宫颈复原满意者601例,达90.0%,治愈率为99.0%。结论:leep术具有操作简单、手术时间短、出血少、并发症少等优点,是治疗CIN的简单、安全且有效的方法,同时因其可保留组织送病检,也是诊断CIN的直接依据。
Objective: To investigate the value of cervical ring excision (leep surgery) in the treatment of cervical intraepithelial neoplasia (CIN). Methods: The patients undergoing colposcopy and cervical biopsy initially diagnosed as CINⅠ-Ⅲ were treated with leep conization. The operative time, intraoperative blood loss, the coincidence rate of postoperative pathological results and preoperative results, and the postoperative follow-up of cervical recovery The clinical efficacy of retrospective analysis. Results: The mean duration of leep surgery for CIN was 5.6 min and the amount of bleeding was 7.8 ml. The coincidence rate of preoperative and postoperative pathological diagnosis was 72.4%, the pathological grade increased 4.0% and the pathological grade decreased 23.6%. Among 668 patients (excluding 5 with hysterectomy and 2 with extensive hysterectomy plus pelvic lymph node dissection), 601 patients satisfied with cervical reconstruction reached 90.0% with a cure rate of 99.0%. Conclusion: The leep technique has the advantages of simple operation, short operative time, less bleeding and less complications. It is a simple, safe and effective method for the treatment of CIN. It is also the direct basis for the diagnosis of CIN because it can preserve the tissue for pathological examination.