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肝细胞性疾病患者有明显血管扩张,几乎所有血管均有动静脉旁路开放,包括皮肤、肌肉、肾、肺、门静脉系统甚至脑等。此种循环改变可能与全身组织的缺氧有关,可导致功能性肾衰竭、肺衰竭、门脉高压及脑水肿。其致病因子不明。可能因胰高糖素和前列腺素,还有局部的组织因素。肝细胞陛疾病,尤其是肝硬化患者,呈高动力循环,表现为明显的血管扩张,本文对此进行讨论。
Hepatocellular disease patients have obvious vasodilation, almost all blood vessels have arteriovenous bypass, including the skin, muscle, kidney, lung, portal vein system and even brain. Such circulatory changes may be associated with systemic hypoxia, leading to functional renal failure, pulmonary failure, portal hypertension and cerebral edema. Its causative agent is unknown. May be due to glucagon and prostaglandins, as well as local tissue factors. Hepatocellular disease, especially in patients with cirrhosis, showed a hyperdynamic circulation with marked vasodilation, which is discussed in this article.