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目的:观察某部特种兵参加27km武装越野考核前后尿清蛋白(ALB)、β2-微球蛋白(β2-MG)、N-乙酰-β-氨基葡萄糖苷酶(NAG)和γ-谷氨酰基转移酶(GGT)水平变化。方法:采用自动生化分析仪测定参加27km武装越野特种兵59例考核前后不同时间点的ALB、β2-MG、NAG和GGT水平。结果:考核后即时尿ALB、β2-MG、NAG和GGT水平显著升高,与考核前比较,差异非常显著(P<0.01);考核后休息8h尿ALB、NAG及GGT水平恢复至考核前水平;休息至次日晨尿β2-MG水平恢复至考核前水平。结论:27km武装越野引发肾功能异常以肾小球滤过屏障损伤和肾小管重吸收功能损伤多见,肾小球滤过屏障损伤休息8h后多可恢复,肾小管重吸收功能损伤恢复时间相对较长。
Objective: To observe the changes of urine albumin (ALB), β2-microglobulin (β2-MG), N-acetyl-β-glucosaminidase (NAG) and γ-glutamyltransferase before or after 27m armed off- Changes in enzyme (GGT) levels. Methods: The levels of ALB, β2-MG, NAG and GGT at different time points before and after assessment were investigated by using automatic biochemistry analyzer. Results: The levels of urinary ALB, β2-MG, NAG and GGT in urine immediately after the examination were significantly higher than those before examination (P <0.01), and the urine ALB, NAG and GGT returned to pre-examination levels ; Rest until the next morning urinary β2-MG levels returned to pre-assessment levels. Conclusion: 27km armed off-road induced renal dysfunction with damage to glomerular filtration barrier and tubular reabsorption more common, glomerular filtration barrier injury rest more 8h after recovery, renal tubular reabsorption recovery time relative Longer.