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一、糖尿病患者神经损害的发病率研究指出,382例胰岛素依赖型糖尿病病人中,症状性糖尿病性神经病的发生率为10.7%,具有明显神经损害体征者占19.6%,神经冲动传导异常者约占所有糖尿病病人的80%。尽管许多糖尿病患者都存在明显的神经机能障碍,但在临床实践中,对约20%具有神经损害症状和体征的病人予以重视,显得更为重要。二、发病机理(一)高血糖与山梨醇和肌醇代谢的关系:糖尿病性神经病神经冲动传导障碍与血糖水平之间呈明显的相关性是勿庸置疑的。近年来,
First, the incidence of neurological damage in diabetic study pointed out that 382 cases of insulin-dependent diabetes mellitus, the incidence of symptomatic diabetic neuropathy was 10.7%, 19.6% of patients with significant signs of nerve damage, nerve impulse conduction abnormalities accounted for about 80% of all diabetic patients. Although many diabetic patients have significant neurological dysfunctions, it is even more important in clinical practice to focus attention on about 20% of patients with signs and symptoms of neurological damage. Second, the pathogenesis (a) the relationship between hyperglycemia and sorbitol and inositol metabolism: diabetic neuropathy Nerve impulse conduction disorder and blood glucose levels showed a clear correlation between is beyond doubt. In recent years,