为了探索家蚕病原性微孢子虫作为生物农药的潜力,试验用不同浓度的家蚕微孢子虫(Nose-ma bombycis)对主要农业害虫之一的亚洲玉米螟(Ostrinia furnacalis)3龄幼虫进行室内感染,并测试其室内毒力。结果表明:当家蚕微孢子虫孢子浓度为1.0×107/mL时,玉米螟幼虫死亡率达80%,校正死亡率高达75%;半数致死浓度(LC50)为2.5×105/mL;不同浓度的家蚕微孢子虫对玉米螟幼虫的杀灭效果有极显著差异。说明将家蚕微孢子虫开发为生物农药具有较大潜力。 In order to explore the potential of silkworm pathogenic microsporidia as a bio-pesticide, we tested indoor infection of 3rd instar larvae of Ostrinia furnacalis, one of the major agricultural pests, with different concentrations of Nose-ma bombycis, And test its indoor toxicity. The results showed that when the concentration of Nosema baumannii was 1.0 × 107 / mL, the mortality of Ostrinia furnacalis larvae reached 80%, the corrected mortality was 75%; the LC50 was 2.5 × 105 / mL; Nosema bombycids kill corn borer larvae have very significant differences. The results showed that the development of Nosema bombycis has great potential as a bio-pesticide.