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目的:探讨血肌钙蛋白I(cTnI)指标的变化水平与急性心力衰竭的严重程度及预后的相关性。方法:选择贵州省贵阳市第二人民医院心内科2005年1月～2009年1月105例因急性心力衰竭入院的患者,入院后24h内测定cTnI水平,根据肌钙蛋白水平测定将两组患者分为阳性和阴性组,比较两组患者住院期间的药物使用率、病死率及左室收缩功能。结果:入院时cTnI阳性组病死率为17.4%,阴性组为3.7%,阳性组病死率明显高于阴性组(P<0.05);阳性组患者左室收缩功能明显差于阴性组患者(P<0.001);两组患者的利尿剂、血管扩张药物使用率相比,差异无统计学意义,P>0.05。结论:cTnI阳性可以作为急性心力衰竭严重程度及短期预后的预测指标。
Objective: To investigate the relationship between the level of cTnI and the severity and prognosis of acute heart failure. Methods: From January 2005 to January 2009, 105 patients admitted to the Second People’s Hospital of Guiyang, Guizhou Province from January 2005 to January 2009 were enrolled in this study. The levels of cTnI were measured 24h after admission. According to the level of troponin, two groups of patients Divided into positive and negative groups, compared the two groups of patients during hospital use of drug use, mortality and left ventricular systolic function. Results: The mortality rate of cTnI positive group was 17.4% and the negative group was 3.7%. The case fatality rate of the positive group was significantly higher than that of the negative group (P <0.05). The positive group had significantly lower left ventricular systolic function than the negative group (P < 0.001). There was no significant difference in diuretic and vasodilator use between the two groups (P> 0.05). Conclusion: cTnI positivity can be used as a predictor of the severity of acute heart failure and short-term prognosis.