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背景:Torcetrapib是一种胆固醇酯转运蛋白(CETP)抑制剂,可能通过提高高密度脂蛋白(HDL)胆固醇水平减少动脉粥样硬化性血管疾病。方法:共纳入850例杂合型家族性高胆固醇血症患者,分别在基线和随访时行B型超声检查,以测定颈动脉内膜中层厚度的变化。患
BACKGROUND: Torcetrapib is a cholesterol ester transfer protein (CETP) inhibitor that reduces atherosclerotic vascular disease by increasing high-density lipoprotein (HDL) cholesterol levels. Methods: A total of 850 cases of heterozygous familial hypercholesterolemia were enrolled in this study. Type B ultrasound was performed at baseline and at follow-up to determine the change of carotid intima-media thickness. Suffering