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目的 研究海上大深度饱和潜水对潜水员血浆精氨酸加压素 (AVP)、强啡肽 A(Dyn A)、促肾上腺皮质激素 (ACTH)和促皮质素释放激素 (CRH)含量的影响。方法 用放射免疫法检测 8名潜水员在饱和潜水前后血浆 AVP、Dyn A、ACTH和 CRH的含量。结果 饱和潜水后潜水员血浆 AVP(14 4 8.5± 16 33.6 ) ng/L、Dyn A(4 9.4± 36 .8) ng/L、ACTH(392 .1± 2 4 5 .6 ) ng/L 和 CRH(378.1±4 4 .6 ) ng/L 含量显著或非常显著地高于饱和潜水前 (P<0 .0 5或 <0 .0 1)。结论 大深度饱和潜水能引起潜水员血浆 AVP、Dyn A、ACTH和 CRH含量的改变 ,所观察的 4种神经肽可能参与了大深度饱和潜水引起的机体应激反应
Objective To study the effects of deep deep saturation diving on the levels of plasma arginine vasopressin (AVP), Dyn A, ACTH and corticotropin releasing hormone (CRH) in sea divers. Methods The contents of AVP, Dyn A, ACTH and CRH in plasma of 8 divers before and after saturation diving were detected by radioimmunoassay. Results The results showed that the average plasma levels of AVP (14 4 8.5 ± 16 33.6) ng / L, Dyn A (4 9.4 ± 36.8 ng / L), ACTH (392 ± 2 45.6) ng / L and CRH (378.1 ± 44.6) ng / L was significantly or very significantly higher than before saturation diving (P <0.05 or <0.01). Conclusions Large-scale deep-dive can cause the change of AVP, Dyn A, ACTH and CRH in the diver. The four neuropeptides observed may be involved in the stress response