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目的:观察坤泰胶囊与补佳乐联合治疗子宫全切除术后引起的绝经期综合征患者的临床疗效。方法:随机选取阳江市中医医院2014年4月至2016年4月收治的绝经期综合征患者70例,分为对照组与观察组。对照组35例,给予克龄蒙片进行治疗。观察组35例,给予坤泰胶囊与补佳乐联合治疗。比较2组患者临床疗效及治疗前后激素水平变化。结果:观察组治疗有效率(94.3%)明显高于对照组(77.1%),差异具有统计学意义(P<0.05)。治疗后对照组与观察组雌二醇(E2)、卵泡刺激素(FSH)水平与治疗前比较差异均具有统计学意义(P<0.05),治疗前2组E2、FSH水平比较差异无统计学意义(P>0.05)。治疗后,观察组E2、FSH水平优于对照组,差异具有统计学意义(P<0.05)。结论:采用坤泰胶囊与补佳乐联合治疗绝经期综合征,可显著提高治疗绝经期综合征患者临床疗效,改善其E2、FSH水平。
Objective: To observe the clinical efficacy of KunTai capsule combined with Nongjiale in the treatment of postmenopausal syndrome caused by total hysterectomy. Methods: Seventy patients with menopausal syndrome admitted from April 2014 to April 2016 in Yangjiang Chinese Medicine Hospital were randomly selected and divided into control group and observation group. The control group of 35 cases, given Kelon mask for treatment. The observation group of 35 cases, given kuntai capsule and nadia combined treatment. The clinical efficacy and the changes of hormone levels before and after treatment were compared between the two groups. Results: The effective rate of treatment group (94.3%) was significantly higher than that of control group (77.1%), the difference was statistically significant (P <0.05). After treatment, the levels of estradiol (E2) and follicle stimulating hormone (FSH) in the control group and the observation group were significantly different from those before treatment (P <0.05). There was no significant difference in E2 and FSH levels between the two groups before treatment Significance (P> 0.05). After treatment, the levels of E2 and FSH in the observation group were better than those in the control group, with statistical significance (P <0.05). Conclusion: The combination of Kuntai capsule and Nongjiale treatment of menopausal syndrome, can significantly improve the clinical efficacy of treatment of patients with menopausal syndrome, improve their E2, FSH levels.