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目的探讨小儿喘息性疾病与肺炎支原体感染(MP)的关系及其临床意义。方法放射免疫法对68例喘息性疾病患儿进行MP抗体检测,并对哮喘患儿MP检测阳性者采用大环内酯类药物治疗随访。结果 68例小儿哮喘性疾病MP阳性33例,阳性率48.53%,其中哮喘病18例,阳性9例,治疗后随访完全者7例,哮喘再发严重程度均较治疗前明显改善。结论 MP作为一种致病微生物与哮喘的关系不容忽视,与喘息再发有密切关系,MP作为小儿喘息性疾病诱发因素应予重视。
Objective To investigate the relationship between asthmatic mycoplasma pneumoniae infection (MP) and infantile asthma and its clinical significance. Methods Radioimmunoassay was used to detect MP antibody in 68 children with wheezing diseases and macrolides were followed up in patients with positive MP in children with asthma. Results 68 cases of children with asthma MP positive in 33 cases, the positive rate of 48.53%, of which 18 cases of asthma, positive in 9 cases, followed up completely in 7 cases, the severity of recurrent asthma than before treatment was significantly improved. Conclusion The relationship between MP as a pathogenic microorganism and asthma can not be neglected. It is closely related to recurrent wheezing. MP should be paid more attention as a predisposing factor for asthmatic children.