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病毒性肝炎相关性再障由Lorenz等1955年首次报道。国内外文献报道发病率为0.06％～0.07％,我院连续发现2例病毒性肝炎相关性再障,现报告如下。 病例1:患者,男,14岁,以乏力,尿深黄1周于1998年10月5日收入院。患者1周前在外就餐后出现乏力,小便颜色加深,伴厌油、恶心,曾呕吐胃内容物1次,腹泻3天,为稀黄色大便,无胨子、腹痛,里急后重等,PE:T36.5℃,BP120/80mmHg,神清,全身皮肤粘膜黄染,无出血点、蜘蛛痣等,心肺(一),肝右胁下1.5cm,质软,无触痛。入院后,实验室检查,抗-HBs(+),甲、丙、戊肝抗体(一),Blood-Rt;WBC5.5×10~9/L,RBC4.2×10~(12)/L,BPC175×10~5/L,PT>25。肝功能:ALT2260U/L,AST1169U/L。TBil111.5μmol/L。检查B超:①胆囊壁增厚;②胆囊内胆汁郁结可能,临床经强力宁、苦黄注射液等药物治疗后,复查肝功能:ALT115U/L,AST98U/
Viral hepatitis-related aplasia was first reported by Lorenz et al in 1955. The incidence of domestic and foreign literature was 0.06% ~ 0.07%, 2 consecutive cases of viral hepatitis found in our hospital aplastic anemia, are as follows. Case 1: Patients, male, 14 years old, with weakness, dark urine 1 week in October 5, 1998 income hospital. Patients with fatigue after eating outside 1 week, urine color deepened, with tired of oil, nausea, vomiting stomach contents 1, 3 days of diarrhea, for the stool of yellow, no peptone, abdominal pain, tenesmus, etc., PE: T36. 5 ℃, BP120 / 80mmHg, Shen Qing, whole body skin and mucous membrane yellow dye, no bleeding point, spider nevus, etc., cardiopulmonary (a), the right hepatic lesion 1.5cm, soft, no tenderness. After admission, the laboratory tests showed that anti-HBs (+), A, C and E antibody (a), Blood-Rt; WBC5.5 × 10-9 / L, RBC4.2 × 10-12 / , BPC175 × 10 ~ 5 / L, PT> 25. Liver function: ALT2260U / L, AST1169U / L. TBil 111.5 μmol / L. Check B ultrasound: ① gallbladder wall thickening; ② gallbladder may be cholesthesia, clinically by strong Ning, Ku Huang injection and other drugs, review of liver function: ALT115U / L, AST98U /