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为探讨患妊娠糖尿病(GD)妇女祖父母代的糖尿病发生率,并确定一级亲属有糖尿病是否为后代发展为GD的预示指标,对患GD和胰岛素依赖性(Ⅰ型)糖尿病(IDDM)妇女母代和祖母代IDDM和非胰岛素依赖性(Ⅱ型)糖尿病(NIDDM)的发生率做了调查。在妊娠26～28周间服用50g葡萄糖进行糖耐量试验确诊GD106例,将其与189例患IDDM的妊娠妇女比较母系和父系IDDM和NIDDM发生的家族史。结果发现,GD妇女其母亲糖尿病的发生率明显高于父亲,其母亲和祖母代糖尿病的发生率显著高于父亲和祖父代,母亲NID-DM的发生率显著高于父亲,母亲和祖母代患NIDDM的数量显著高于父亲和祖父代,但GD患者其母系和父系IDDM的发生率无显著差异。在GD母系和父系家族中,NIDDM的发生率显著高于IDDM。患IDDM妇女其父亲和母亲糖尿病的发生率无显著差异,母亲和祖母代患糖尿病的数量与父亲和
To investigate the prevalence of diabetes in grandparental mothers with gestational diabetes (GD) and to determine whether first-degree relatives have diabetes as a predictor of their future development in GD, women with GD and insulin-dependent (type 1) diabetes (IDDM) Generation and grandmothers investigated the incidence of IDDM and non-insulin dependent (type II) diabetes mellitus (NIDDM). In the 26 to 28 weeks gestation taking 50g glucose glucose tolerance test confirmed GD106 cases, with 189 cases of pregnant women with IDDM maternal and paternal IDDM and NIDDM family history. The results showed that the incidence of diabetes in mothers of GD women was significantly higher than that of fathers, the incidence of diabetes on mother and grandmother was significantly higher than that of fathers and grandparents, and the incidence of mothers NID-DM was significantly higher than that of fathers, mothers and grandmothers The number of NIDDM was significantly higher than that of father and grandfather, but there was no significant difference in the incidence of IDDM between maternal and paternal in GD patients. In the GD maternal and paternal families, the incidence of NIDDM was significantly higher than IDDM. There was no significant difference in the incidence of diabetes between IDDM women and their father and mother, and the number of mothers and grandmothers on behalf of diabetes mellitus and father and