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在疟疾流行地区,对疟疾有自然免疫力的妇女在怀孕期间和产后直至6周内应该服用抗疟预防药,这是因为她们在这一时期的免疫系统功能下降。在疟疾流行区域无免疫力的妇女在怀孕期间及哺乳期应劝告服用抗疟预防药。但缺乏抗疟药物向人乳中排泄的报道。一项研究在同时服用氯喹和氨苯砜及乙胺嘧啶复合剂后检测了氯喹、氨苯砜和乙胺嘧啶向人乳中的排泄。这种合并治疗法被推荐为这一地区的抗疟预防措施,在这地区中流行着对多种药物抵抗的恶性疟原虫和间日疟原虫株。
In malaria-endemic areas, women with natural immunity to malaria should take antimalarial prophylaxis during pregnancy and up to 6 weeks after delivery because of their diminished immune system during this period. Women with no immunity in malaria-endemic areas should be advised to take antimalarial prophylaxis during pregnancy and during lactation. But the lack of anti-malarial drugs to human milk excretion reported. One study examined the excretion of chloroquine, dapsone and pyrimethamine into human milk after taking both chloroquine and dapsone and pyrimethamine compounds. This combination therapy is recommended as an anti-malarial prophylaxis in the region where P. falciparum and P. vivax are resistant to multiple drugs.