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目的探讨普米克联合博利康尼及沐舒坦气泵吸入治疗毛细支气管炎的临床疗效。方法将80例确诊毛细支气管炎患儿分为对照组与治疗组各40例。对照组采用抗感染、止咳、化痰等综合治疗,治疗组在常规治疗基础上加入普米克1 mg/次、博利康尼2.5 mg/次及沐舒坦15 mg/次,配置成混合溶液,应用空气压缩气泵吸入治疗。每次10~15 min,根据病情每日2~4次,疗程3~7 d。对比2组气促好转、心率恢复正常、喘鸣音消失、湿啰音消失、咳嗽消失情况。统计学方法运用SPSS 11.0统计软件进行数据处理,计量资料用(x±s)表示,组间参数比较采用t检验。结果治疗组在改善呼吸系统症状,降低气道阻力,缩短病程方面效果明显优于对照组。治疗组气促好转、心率恢复正常、喘鸣音消失、湿啰音消失、咳嗽消失时间与对照组比较明显缩短,差异均有统计学意义(P均<0.01)。结论普米克联合博利康尼及沐舒坦气泵吸入治疗可有效改善毛细支气管炎症状,改善肺功能,疗效确切。
Objective To investigate the clinical efficacy of pulmicort combined with boliadine and mucosolvan inhalation in the treatment of bronchiolitis. Methods 80 children diagnosed with bronchiolitis were divided into control group and treatment group, 40 cases each. The patients in the control group were treated with anti-infection, cough-stopping and phlegm-resolving therapy. The patients in the treatment group were given Pulmicort 1 mg / time, BoliCanconi 2.5 mg / time and ambroxol 15 mg / time on the basis of routine treatment. Air compression pump inhalation therapy. Each 10 ~ 15 min, according to the disease 2 to 4 times daily, course of treatment 3 ~ 7 d. Contrast two groups of breathlessness, heart rate returned to normal, wheezing disappeared, wet rales disappeared, cough disappeared. Statistical methods SPSS 11.0 statistical software for data processing, measurement data (x ± s) that the comparison between groups using t test. Results The treatment group was significantly better than the control group in improving respiratory symptoms, reducing airway resistance and shortening the course of disease. In the treatment group, the improvement of breathlessness, normal heart rate, disappearance of wheezing, disappearance of wet rales and disappearance of cough were significantly shorter than those of the control group (all P <0.01). Conclusions Pulmicortes combined with boliadine and mucosolvan pump inhalation therapy can effectively improve the symptoms of bronchiolitis and improve lung function with definite curative effect.