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目的探讨胸腔中心静脉导管间断引流联合尿激酶,治疗结核性胸腔积液的疗效。方法将B超提示深度50mm以上结核性胸腔积液病人120例,随机分为治疗组60例和对照组60例。两组均足量抗结核药物治疗;治疗组胸腔置中心静脉导管间隔6～8 h引流一次,对照组胸腔置中心静脉导管引流,每日一次;两组均待无胸水流出,透视未见胸腔积液影或仅剩少量积液影时,经引流管注入尿激酶10～20万u+0.9%NS 60 mL,夹管1 h后引流。结果与对照组比较,治疗组胸腔积液吸收时间显著缩短。结论胸腔中心静脉导管间断引流联合尿激酶,治疗结核性胸腔积液的方法安全、疗效好,值得临床推广应用。
Objective To investigate the curative effect of thoracic central venous catheter drainage combined with urokinase in the treatment of tuberculous pleural effusion. Methods A total of 120 patients with tuberculous pleural effusion above 50mm in depth of B ultrasound were randomly divided into treatment group (60 cases) and control group (60 cases). Both groups were treated with adequate anti-TB drugs. The patients in the treatment group were placed in the central venous catheter 6 to 8 hours after drainage. The control group received central venous catheter drainage once a day. Both groups were treated with pleural effusion without fluoroscopy Accumulation of fluid or only a small amount of fluid shadow, the urokinase 10 ~ 200,000 u + 0.9% NS 60 ml drainage tube after drainage for 1 h after drainage. Results Compared with the control group, the absorption time of pleural effusion in the treatment group was significantly shortened. Conclusions Thoracic central venous catheter drainage combined with urokinase is safe and effective in the treatment of tuberculous pleural effusion, which is worthy of clinical application.