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自由基(free radical,FR)可以引发生物膜脂质过氧化、蛋白质变性和酶失活等毒性作用。自由基的损伤作用影响机体抗氧化能力,是许多疾病损伤机体的共同通路。在碘致甲状腺疾病中,氧化损伤起重要作用。放射性同位素示踪表明,摄入的碘可分布到甲状腺及其以外的组织,因此,碘摄入异常对机体的氧化损伤可能是全身性的。不同碘量(低碘、高碘)和不同碘剂(KIO3、KI)对机体抗氧化能力的影响效果不完全相同,
Free radicals (FR) can induce biofilm lipid peroxidation, protein denaturation and enzyme inactivation and other toxic effects. The role of free radicals damage the body’s antioxidant capacity, is the common pathways of many diseases damage the body. In iodine-induced thyroid disease, oxidative damage plays an important role. Radioisotope tracer shows that iodine intake can be distributed to the thyroid gland and other tissues, therefore, oxidative damage to the body by abnormal iodine intake may be systemic. The effects of different iodine levels (low iodine, high iodine) and different iodine agents (KIO3, KI) on the antioxidant capacity of the body are not exactly the same,