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有些高血压患者对不同剂量的多种药物单独或联合治疗均无显效。因此近来推荐应用血管紧张素转化酶抑制剂甲巯丙脯酸(Captopril)治疗严重高血压受到重视。该药能抑制血管紧张素Ⅰ转化为血管紧张素Ⅱ,通过影响肾素——血管紧张素系统发挥抗高血压效应。作者证实甲巯丙脯酸伍用肾性利尿剂速尿,获得持续控制难以驾驭的重症高血压的满意疗效。接受治疗的12例患者,5例双侧视网膜出血,其中4例合并视神经乳突水肿。2例
Some hypertensive patients with different doses of a variety of drugs alone or in combination therapy were not effective. Therefore recently recommended the application of angiotensin-converting enzyme inhibitor captopril treatment of severe hypertension attention. The drug inhibits the conversion of angiotensin I to angiotensin II and exerts its antihypertensive effect by affecting the renin-angiotensin system. The authors confirmed that captopril with renal diuretic furosemide, sustained control of difficult to control the serious effect of hypertension. Twelve patients were treated, and five had bilateral retinal hemorrhage. Four of them had optic papilloma. 2 cases