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目前,大多数医院在溶解青、链霉素时均按《基础护理学》的规定:将青霉素40万u用2 ml生理盐水溶解,每ml含20万u;链霉素100万u用生理盐水3.5 ml溶解,每ml含25万u,但在临床工作中按此法操作时,不难发现溶解后的青、链霉素溶液(溶质+溶剂的总容积)均比原溶剂(生理盐水)的容积稍大。也就是说青霉素40万u用2 ml生理盐水溶解后不是2ml而是多于2ml;链霉素用3.5ml生理盐水溶解后也多于4 ml。这显然是青、链霉素溶解后也占了一定的容积。为此我们取了国内几个厂家生产的青、链霉素作溶解实验,观察其容积增加的情况及浓度变化情况。证明此容积的增加对药物的浓度是有一定的影响的。
At present, most hospitals dissolve green and streptomycin according to the “basic nursing science” provisions: the penicillin 400,000 u with 2 ml of saline dissolved per ml containing 200,000 u; streptomycin 1 million u with physiology Saline 3.5 ml dissolved, containing 250000 u per ml, but in clinical work according to this method is not difficult to find dissolved green, streptomycin solution (solute + total volume of solvent) than the original solvent (saline ) The volume slightly larger. That is to say 400,000 u of penicillin dissolved in 2 ml of physiological saline is not 2ml but more than 2ml; streptomycin dissolved more than 4ml with 3.5ml of physiological saline. This is clearly green, streptomycin dissolved also accounted for a certain volume. To this end, we took the green, streptomycin produced by several domestic manufacturers for dissolution experiments to observe the situation of its volume increase and concentration changes. Proved that the increase in volume of the concentration of the drug has a certain impact.