以前作者曾用大体标本染色技术发现生前不吸烟和无慢性气管炎的喉标本中一半有鳞状上皮化生。Scalzitti认为患慢性气管炎者喉部鳞状上皮化生大部分在声门上区。Auerbac h等看到吸烟者声带上皮比不吸烟者有较多的不典型细胞核,而这种变化也偶见于声门下区。Ryan等检查1500例吸烟者尸体的喉部,见室带表面有鳞状上皮化生,圆细胞浸润和粘膜增生,但声门下区则少见以上变化。本文报道用大体标本染色法观察声门下区鳞状上皮化生的范围和发生率。研究了226例尸体标本,生前吸烟者121例,不吸烟者105例。在不 Previously, the authors used gross specimen staining techniques to detect squamous metaplasia in half of the non-smoking and non-chronic bronchitis specimens. Scalzitti believes that most of the laryngeal squamous metaplasia in chronic bronchitis occurs in the supraglottic region. Auerbac h, etc. See the smoker vocal cord epithelium than non-smokers have more atypical nuclei, and this change is occasionally found in the subglottic area. Ryan et al examined the larynx of 1500 smokers and found squamous metaplasia, round cell infiltration and mucosal hyperplasia in the ventricular zone, but the subglottic region was less common. This article reports the gross specimen staining method to observe the extent and incidence of squamous metaplasia in the subglottic area. 226 cadaver specimens were studied, 121 pre-existing smokers and 105 non-smokers. No