从金环蛇毒中分离到一个神经毒—组分Ⅸ。该组分阻断小鸡颈二腹肌神经肌肉接头传递;阻断标本对乙酰胆碱的反应,标本对直接电刺激以及对高浓度钾离子的反应性仍然存在;组分Ⅸ使蛙缝匠肌终板电位,微终板电位振幅逐渐减小,最后完全消失;但不影响微终板电位的发放频率,也不影响肌纤维的静息膜电位。实验表明组分Ⅸ是作用于突触后膜的神经毒。 A neurotoxic agent, component IX, was isolated from the. This component blocks the transmission of the neuromuscular junction of the biceps muscle of the chick; intercepts the reaction of the sample to acetylcholine, and the reactivity of the specimen to the direct electrical stimulation and the high concentration of potassium ions still exists; Plateau potential, micro-plate potential amplitude gradually reduced, and finally completely disappeared; but does not affect the release of micro-endplate potential, it does not affect the resting membrane potential of muscle fibers. Experiments show that component IX is a neurotoxic effect on the postsynaptic membrane.