一些学者强调了变形链球菌具有集居于牙面及造成龋病的能力。已经证实,变链对牙面的粘附是由于葡糖基转移酶合成的不溶性胞外多糖所致。此外,Hotz等人指出,变聚糖对限制牙菌斑扩散的性质大有帮助,因此推测水解这些葡聚糖的酶对预防龋齿应该有效。在离体试验中很早就已证实,由trichoderma harzianum OMZ779所产生的 Some scholars emphasize Streptococcus mutans have the ability to live in the tooth surface and cause caries. It has been demonstrated that the alteration of the chain adhesion to the tooth surface is due to glucosyltransferase synthesis of insoluble exopolysaccharides. In addition, Hotz et al. Indicate that the variable glycans greatly help to limit the spread of plaque, so it is hypothesized that the enzymes that hydrolyze these glucans should be effective in preventing dental caries. It has long been demonstrated in vitro that produced by trichoderma harzianum OMZ779